Coen lab publications on PubMed
Recent publications include:
Chen H, Lye M, Gorgulla C, Ficarro SB, Cuny GD, Scott DA, Wu F, Rothlauf PW, Wang X, Fernandez R, Pesola JM, Draga S, Marto JA, Hogle JM, Arthanari H, Coen DM. A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex. PLOS Pathogens 2023;19:e1011781.
Deng Y, Lin Y, Chen S, Xiang Y, Chen H, Qi S, Oh HS, Das B, Komazin-Meredith G, Pesola JM, Knipe DM, Coen DM, Pan D. Neuronal miR-9 promotes herpes simplex virus 1 epigenetic silencing and latency by repressing Oct-1 and Onecut family genes. Nat Commun 2024;15:1991.
Lawler JL, Terrell S, Coen DM. The conserved RNP motif of the herpes simplex virus 1 family B DNA polymerase is crucial for viral DNA synthesis but not polymerase activity. Virology 2024;594:11035.
Shankar S, Pan J, Yang P, Bian Y, Oroszlán G, Yu Z, Mukherjee P, Filman DJ, Hogle JM, Shekhar M, Coen DM, Abraham J. Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance. Cell 2024:187:5572-5586.
Oh H, Chou S-F, Raja P, Shim J, Das B, Pesola JM, Romero N, Lee JS, Ng A, Buttermore ED, Church G, Woolf CJ, Coen DM, Knipe DM. Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1. mBio 2025: Aug 18:e0187125. doi: 10.1128/mbio.01871-25. Epub ahead of print.
Canova P, Katzenell S, Cerón S, Charron AJ, Pesola JM, Oh HS, Coen DM, Knipe DM, Leib DA. Herpes simplex virus 1 ICP34.5 acts to maintain latency in human and mouse neurons. Virology 2025;110652.